Source Naturals Calcium D-Glucarate includes the patented compound glucarate which has been shown to enhance the major detoxification pathways in the body. Calcium D-Glucarate, the calcium salt of D-glucaric acid, is found naturally in the human body and in a variety of fruits and vegetables. Animal studies have shown that high doses of calcium D-glucarate inhibit beta-glucuronidase, thereby enhancing the process of glucuronidation, in which foreign organic compounds, fat-soluble toxins and excess steroid hormones such as estrogen are detoxified and excreted from our bodies.