Hawthorn (Crataegus oxyacantha) has been used for centuries to aid circulation. Clinical research has identified the beneficial compounds responsible for Hawthorn’s activity. These compounds include flavonoids, such as vitexin 4’-rhamnoside, O-glycosides, luteolin-7 glucoside, hyperoside, quercetin and rutin. The powerful antioxidants in Hawthorn protect the cells of the cardiovascular system from free radicals.