SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect the brain biochemistry and joint health. Numerous studies have indicated that SAMe can Enhance to temporarily alleviate aches and Discomforts resulting from overexertion or stress. Therefore SAMe is an all natural product that can be part o f a nutritional program for Discomfort management. In addition, because it plays an important role in the regulation of mood. NOW SAMe is enteric coated, which makes it very well tolerated and protects it from degradation.