Best Stabilized R-Lipoic Acid contains K-RALA , the potassium salt of R-Lipoic acid (RLA). K-RALA is the stabilized form of RLA that won't degrade at high temperatures, is more soluble than regular RLA and has a higher bioavailability. K-RALA enhances the release of RLA in the body. R-Lipoic Acid is chemically considered to be a weak acid. A principle of pharmacology is that salts of weak acids have a much higher solubility in water than the weak acid alone.1 By taking the potassium salt of RLA, it's solubility is increased and it has an improved dissolution in the body. This is the principle upon which K-RALA was founded. Pure RLA is a very unstable molecule that has a tendency to polymerize with exposure to heat, light and moisture. RLA is also hygroscopic, or water-seeking. This presents problems for those wishing to supplement with RLA. Any of these conditions can lead to deactivation of the beneficial activity. K-RALA R-Lipoic acid is known to be more stable, more soluble and less likely to polymerize than pure RLA.